This, the 53rd issue of Transactions on Large-scale Data and Knowledge-centered Systems, contains six fully revised selected regular papers. Topics covered include time series management from edge to cloud, segmentation for time series representation, similarity research, semantic similarity in a taxonomy, linked data semantic distance, linguistics-informed natural language processing, graph neural network, protected features, imbalanced data, causal consistency in distributed databases, actor model, and elastic horizontal scalability. ![](https://www.irit.fr/tldks/wp-content/uploads/2018/07/lncs.jpg) LNCS 13840
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